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ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer
The Serine–Glycine–One-Carbon (SGOC) pathway is pivotal in multiple anabolic processes. Expression levels of SGOC genes are deregulated under tumorigenic conditions, suggesting participation of oncogenes in deregulating the SGOC biosynthetic pathway. However, the underlying mechanism remains elusive...
Autores principales: | Li, Kai, Wu, Jian-lin, Qin, Baifu, Fan, Zongmin, Tang, Qin, Lu, Weisi, Zhang, Haipeng, Xing, Fan, Meng, Manqi, Zou, Shaomin, Wei, Wenxia, Chen, Honglei, Cai, Jian, Wang, Huaiming, Zhang, Hui, Cai, Jiayue, Fang, Ling, Bian, Xiqing, Chen, Chuangqi, Lan, Ping, Ghesquière, Bart, Fang, Lekun, Lee, Mong-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015059/ https://www.ncbi.nlm.nih.gov/pubmed/31772275 http://dx.doi.org/10.1038/s41422-019-0257-1 |
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