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The GSK-3β/β-catenin signaling pathway is involved in HMGB1-induced chondrocyte apoptosis and cartilage matrix degradation

Knee osteoarthritis (KOA) is a common joint disease with a high incidence rate among middle-aged and elderly individuals. However, the precise underlying pathological mechanisms and effective treatment of this disease remain to be determined. To explore the effect of high mobility group box 1 (HMGB1...

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Detalles Bibliográficos
Autores principales: Shu, Zhiyong, Miao, Xiaogang, Tang, Tainhua, Zhan, Peng, Zeng, Langqing, Jiang, Yuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015138/
https://www.ncbi.nlm.nih.gov/pubmed/31922219
http://dx.doi.org/10.3892/ijmm.2020.4460