mTORC1 signalling is not essential for the maintenance of muscle mass and function in adult sedentary mice

BACKGROUND: The balance between protein synthesis and degradation (proteostasis) is a determining factor for muscle size and function. Signalling via the mammalian target of rapamycin complex 1 (mTORC1) regulates proteostasis in skeletal muscle by affecting protein synthesis and autophagosomal prote...

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Detalles Bibliográficos
Autores principales: Ham, Alexander S., Chojnowska, Kathrin, Tintignac, Lionel A., Lin, Shuo, Schmidt, Alexander, Ham, Daniel J., Sinnreich, Michael, Rüegg, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015237/
https://www.ncbi.nlm.nih.gov/pubmed/31697050
http://dx.doi.org/10.1002/jcsm.12505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015237/
https://www.ncbi.nlm.nih.gov/pubmed/31697050
http://dx.doi.org/10.1002/jcsm.12505

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