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Serum amyloid A1 mediates myotube atrophy via Toll‐like receptors

BACKGROUND: Critically ill patients frequently develop muscle atrophy and weakness in the intensive‐care‐unit setting [intensive care unit‐acquired weakness (ICUAW)]. Sepsis, systemic inflammation, and acute‐phase response are major risk factors. We reported earlier that the acute‐phase protein seru...

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Detalles Bibliográficos
Autores principales: Hahn, Alexander, Kny, Melanie, Pablo‐Tortola, Cristina, Todiras, Mihail, Willenbrock, Michael, Schmidt, Sibylle, Schmoeckel, Katrin, Jorde, Ilka, Nowak, Marcel, Jarosch, Ernst, Sommer, Thomas, Bröker, Barbara M., Felix, Stephan B., Scheidereit, Claus, Weber‐Carstens, Steffen, Butter, Christian, Luft, Friedrich C., Fielitz, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015249/
https://www.ncbi.nlm.nih.gov/pubmed/31441598
http://dx.doi.org/10.1002/jcsm.12491