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Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components. The two components, MdtB and MdtC are homologs, therefore i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015380/ https://www.ncbi.nlm.nih.gov/pubmed/32050009 http://dx.doi.org/10.1371/journal.pone.0228877 |