Transthyretin-Binding Activity of Complex Mixtures Representing the Composition of Thyroid-Hormone Disrupting Contaminants in House Dust and Human Serum

BACKGROUND: House dust contains many organic contaminants that can compete with the thyroid hormone (TH) thyroxine ([Formula: see text]) for binding to transthyretin (TTR). How these contaminants work together at levels found in humans and how displacement from TTR in vitro relates to in vivo [Formu...

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Detalles Bibliográficos
Autores principales: Hamers, Timo, Kortenkamp, Andreas, Scholze, Martin, Molenaar, Douwe, Cenijn, Peter H., Weiss, Jana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015555/
https://www.ncbi.nlm.nih.gov/pubmed/32003587
http://dx.doi.org/10.1289/EHP5911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015555/
https://www.ncbi.nlm.nih.gov/pubmed/32003587
http://dx.doi.org/10.1289/EHP5911

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