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Transthyretin-Binding Activity of Complex Mixtures Representing the Composition of Thyroid-Hormone Disrupting Contaminants in House Dust and Human Serum

BACKGROUND: House dust contains many organic contaminants that can compete with the thyroid hormone (TH) thyroxine ([Formula: see text]) for binding to transthyretin (TTR). How these contaminants work together at levels found in humans and how displacement from TTR in vitro relates to in vivo [Formu...

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Detalles Bibliográficos
Autores principales:	Hamers, Timo, Kortenkamp, Andreas, Scholze, Martin, Molenaar, Douwe, Cenijn, Peter H., Weiss, Jana M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Environmental Health Perspectives 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015555/ https://www.ncbi.nlm.nih.gov/pubmed/32003587 http://dx.doi.org/10.1289/EHP5911

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