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Osteogenic preconditioning in perfusion bioreactors improves vascularization and bone formation by human bone marrow aspirates
Cell-derived extracellular matrix (ECM) provides a niche to promote osteogenic differentiation, cell adhesion, survival, and trophic factor secretion. To determine whether osteogenic preconditioning would improve the bone-forming potential of unfractionated bone marrow aspirate (BMA), we perfused ce...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015678/ https://www.ncbi.nlm.nih.gov/pubmed/32095526 http://dx.doi.org/10.1126/sciadv.aay2387 |