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Specificity and mutagenesis bias of the mycobacterial alternative mismatch repair analyzed by mutation accumulation studies

The postreplicative mismatch repair (MMR) is an almost ubiquitous DNA repair essential for maintaining genome stability. It has been suggested that Mycobacteria have an alternative MMR in which NucS, an endonuclease with no structural homology to the canonical MMR proteins (MutS/MutL), is the key fa...

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Detalles Bibliográficos
Autores principales: Castañeda-García, A., Martín-Blecua, I., Cebrián-Sastre, E., Chiner-Oms, A., Torres-Puente, M., Comas, I., Blázquez, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015689/
https://www.ncbi.nlm.nih.gov/pubmed/32095527
http://dx.doi.org/10.1126/sciadv.aay4453