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Upregulation of miR-34c after silencing E2F transcription factor 1 inhibits paclitaxel combined with cisplatin resistance in gastric cancer cells

BACKGROUND: MicroRNA 34c (miR-34c) has been reported to be associated with malignant types of cancer, however, it remains unknown whether miR-34c is involved in chemoresistance in gastric cancer (GC). AIM: To investigate the effect of miR-34c and its upstream transcription factor E2F1 on paclitaxel...

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Detalles Bibliográficos
Autores principales: Zheng, Hong, Wang, Jin-Jing, Yang, Xiao-Rong, Yu, Yong-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015722/
https://www.ncbi.nlm.nih.gov/pubmed/32089626
http://dx.doi.org/10.3748/wjg.v26.i5.499