Population pharmacokinetics of a triple‐secured fibrinogen concentrate administered to afibrinogenaemic patients: Observed age‐ and body weight‐related differences and consequences for dose adjustment in children

AIMS: The pharmacokinetics (PK) of a triple‐secured fibrinogen concentrate (FC) was assessed in patients ≥40 kg by noncompartmental analysis over a period of 14 days with multiple blood samples. Limited PK time point assessments in children lead to consideration of using Bayesian estimation for paed...

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Detalles Bibliográficos
Autores principales: Bellon, Anne, Fuseau, Eliane, Roumanie, Olivier, Lamazure, Jennifer, Stevens, Wil, Dahmane, Amel, Barthez‐Toullec, Malika, Golly, Dominique, Henriet, Céline, Bridey, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015754/
https://www.ncbi.nlm.nih.gov/pubmed/31658379
http://dx.doi.org/10.1111/bcp.14147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015754/
https://www.ncbi.nlm.nih.gov/pubmed/31658379
http://dx.doi.org/10.1111/bcp.14147

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