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A Comparative Analysis of Single-Cell Transcriptome Identifies Reprogramming Driver Factors for Efficiency Improvement

Terminally differentiated somatic cells can be reprogrammed into a totipotent state through somatic cell nuclear transfer (SCNT). The incomplete reprogramming is the major reason for developmental arrest of SCNT embryos at early stages. In our studies, we found that pathways for autophagy, endocytos...

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Detalles Bibliográficos
Autores principales: Li, Hanshuang, Song, Mingmin, Yang, Wuritu, Cao, Pengbo, Zheng, Lei, Zuo, Yongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015826/
https://www.ncbi.nlm.nih.gov/pubmed/32045876
http://dx.doi.org/10.1016/j.omtn.2019.12.035