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Novel Engineered Programmable Systems for ADAR-Mediated RNA Editing
One of the most prevalent forms of post-transcriptional RNA modification is the conversion of adenosine-to-inosine (A-to-I), mediated by adenosine deaminase acting on RNA (ADAR) enzymes. The advent of the CRISPR/Cas systems inspires researchers to work actively in the engineering of programmable RNA...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Society of Gene & Cell Therapy
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015837/ https://www.ncbi.nlm.nih.gov/pubmed/32044725 http://dx.doi.org/10.1016/j.omtn.2019.12.042 |