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Designing chimeric enzymes inspired by fungal cellulosomes

Cellulosomes are synthesized by anaerobic bacteria and fungi to degrade lignocellulose via synergistic action of multiple enzymes fused to a protein scaffold. Through templating key protein domains (cohesin and dockerin), designer cellulosomes have been engineered from bacterial motifs to alter the...

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Detalles Bibliográficos
Autores principales: Gilmore, Sean P., Lillington, Stephen P., Haitjema, Charles H., de Groot, Randall, O'Malley, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015840/
https://www.ncbi.nlm.nih.gov/pubmed/32083193
http://dx.doi.org/10.1016/j.synbio.2020.01.003