Kir6.2-D323 and SUR2A-Q1336: an intersubunit interaction pairing for allosteric information transfer in the K(ATP) channel complex

ATP-sensitive potassium (K(ATP)) channels are widely expressed and play key roles in many tissues by coupling metabolic state to membrane excitability. The SUR subunits confer drug and enhanced nucleotide sensitivity to the pore-forming Kir6 subunit, and so information transfer between the subunits...

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Detalles Bibliográficos
Autores principales: Brennan, Sean, Rubaiy, Hussein N., Imanzadeh, Saba, Reid, Ruth, Lodwick, David, Norman, Robert I., Rainbow, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015859/
https://www.ncbi.nlm.nih.gov/pubmed/31957808
http://dx.doi.org/10.1042/BCJ20190753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015859/
https://www.ncbi.nlm.nih.gov/pubmed/31957808
http://dx.doi.org/10.1042/BCJ20190753

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