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A Targeted Quantitative Proteomic Method Revealed a Substantial Reprogramming of Kinome during Melanoma Metastasis

Kinases are involved in numerous critical cell signaling processes, and dysregulation in kinase signaling is implicated in many types of human cancers. In this study, we applied a parallel-reaction monitoring (PRM)-based targeted proteomic method to assess kinome reprogramming during melanoma metast...

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Detalles Bibliográficos
Autores principales: Miao, Weili, Li, Lin, Liu, Xiaochuan, Qi, Tianyu F., Guo, Lei, Huang, Ming, Wang, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015909/
https://www.ncbi.nlm.nih.gov/pubmed/32051510
http://dx.doi.org/10.1038/s41598-020-59572-5