SIRT1 inhibits chemoresistance and cancer stemness of gastric cancer by initiating an AMPK/FOXO3 positive feedback loop

Chemotherapy is the standard care for patients with gastric cancer (GC); however, resistance to existing drugs has limited its success. The persistence of cancer stem cells (CSCs) is considered to be responsible for treatment failure. In this study, we demonstrated that SIRT1 expression was signific...

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Detalles Bibliográficos
Autores principales: An, Yifei, Wang, Bo, Wang, Xin, Dong, Guoying, Jia, Jihui, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015918/
https://www.ncbi.nlm.nih.gov/pubmed/32051395
http://dx.doi.org/10.1038/s41419-020-2308-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015918/
https://www.ncbi.nlm.nih.gov/pubmed/32051395
http://dx.doi.org/10.1038/s41419-020-2308-4

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