The scaffold protein IQGAP1 is crucial for extravasation and metastasis

IQGAP1 is a scaffold protein involved in a range of cellular activities, including migration, invasion, adhesion and proliferation. It is also oncogenic in a variety of cancers, promoting primary tumor growth and invasiveness. However, the role of IQGAP1 in tumor progression and metastasis remains u...

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Detalles Bibliográficos
Autores principales: Hebert, Jess D., Tian, Chenxi, Lamar, John M., Rickelt, Steffen, Abbruzzese, Genevieve, Liu, Xiaotie, Hynes, Richard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015931/
https://www.ncbi.nlm.nih.gov/pubmed/32051509
http://dx.doi.org/10.1038/s41598-020-59438-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015931/
https://www.ncbi.nlm.nih.gov/pubmed/32051509
http://dx.doi.org/10.1038/s41598-020-59438-w

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