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6-Gingerol induces cell-cycle G1-phase arrest through AKT–GSK 3β–cyclin D1 pathway in renal-cell carcinoma

PURPOSE: 6-Gingerol, a major biochemical and pharmacological active ingredient of ginger, has shown anti-inflammatory and antitumor activities against various cancers. Searching for natural products with fewer side effects for developing adjunctive therapeutic options is necessary. METHODS: The effe...

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Detalles Bibliográficos
Autores principales: Xu, Shan, Zhang, Haibao, Liu, Tianjie, Yang, Wenjie, Lv, Wei, He, Dalin, Guo, Peng, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015962/
https://www.ncbi.nlm.nih.gov/pubmed/31832810
http://dx.doi.org/10.1007/s00280-019-03999-9