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A Novel Role for Necroptosis in the Pathogenesis of Necrotizing Enterocolitis

BACKGROUND & AIMS: Necrotizing enterocolitis (NEC) is a devastating disease of premature infants characterized by Toll-like receptor 4 (TLR4)-dependent intestinal inflammation and enterocyte death. Given that necroptosis is a proinflammatory cell death process that is linked to bacterial signali...

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Detalles Bibliográficos
Autores principales: Werts, Adam D., Fulton, William B., Ladd, Mitchell R., Saad-Eldin, Ali, Chen, Yue X., Kovler, Mark L., Jia, Hongpeng, Banfield, Emilyn C., Buck, Rachael H., Goehring, Karen, Prindle, Thomas, Wang, Sanxia, Zhou, Qinjie, Lu, Peng, Yamaguchi, Yukihiro, Sodhi, Chhinder P., Hackam, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015998/
https://www.ncbi.nlm.nih.gov/pubmed/31756560
http://dx.doi.org/10.1016/j.jcmgh.2019.11.002