Overexpression of alpha-synuclein promotes both cell proliferation and cell toxicity in human SH-SY5Y neuroblastoma cells

Alpha-Synuclein (aSyn) is a chameleon-like protein. Its overexpression and intracellular deposition defines neurodegenerative α-synucleinopathies including Parkinson’s disease. Whether aSyn up-regulation is the cause or the protective reaction to α-synucleinopathies remains unresolved. Remarkably, t...

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Detalles Bibliográficos
Autores principales: Rodríguez-Losada, Noela, de la Rosa, Javier, Larriva, María, Wendelbo, Rune, Aguirre, José A., Castresana, Javier S., Ballaz, Santiago J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016025/
https://www.ncbi.nlm.nih.gov/pubmed/32071790
http://dx.doi.org/10.1016/j.jare.2020.01.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016025/
https://www.ncbi.nlm.nih.gov/pubmed/32071790
http://dx.doi.org/10.1016/j.jare.2020.01.009

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