Binding and Structural Properties of DNA Aptamers with VEGF-A-Mimic Activity

Vascular endothelial growth factors (VEGFs) are hypoxia-inducible secreted proteins to promote angiogenesis, in which VEGF-A is an important molecule that binds and activates VEGF receptor-1 (VEGFR-1) and VEGFR-2. In this study, two DNA aptamers, Apt01 and Apt02, were successfully isolated by altern...

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Detalles Bibliográficos
Autores principales: Yoshitomi, Toru, Hayashi, Misako, Oguro, Takumi, Kimura, Keiko, Wayama, Fumiya, Furusho, Hitoshi, Yoshimoto, Keitaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016029/
https://www.ncbi.nlm.nih.gov/pubmed/32059340
http://dx.doi.org/10.1016/j.omtn.2019.12.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016029/
https://www.ncbi.nlm.nih.gov/pubmed/32059340
http://dx.doi.org/10.1016/j.omtn.2019.12.034

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