TMEM16A Ca(2+)-activated Cl(−) channel inhibition ameliorates acute pancreatitis via the IP(3)R/Ca(2+)/NFκB/IL-6 signaling pathway

TMEM16A Ca(2+)-activated Cl(−) channels are expressed in pancreatic acinar cells and participate in inflammation-associated diseases. Whether TMEM16A contributes to the pathogenesis of acute pancreatitis (AP) remains unknown. Here, we found that increased TMEM16A expression in the pancreatic tissue...

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Detalles Bibliográficos
Autores principales: Wang, Qinghua, Bai, Lichuan, Luo, Shuya, Wang, Tianyu, Yang, Fan, Xia, Jialin, Wang, Hui, Ma, Ke, Liu, Mei, Wu, Shuwei, Wang, Huijie, Guo, Shibin, Sun, Xiaohong, Xiao, Qinghuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016042/
https://www.ncbi.nlm.nih.gov/pubmed/32071789
http://dx.doi.org/10.1016/j.jare.2020.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016042/
https://www.ncbi.nlm.nih.gov/pubmed/32071789
http://dx.doi.org/10.1016/j.jare.2020.01.006

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