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Effects of the Positive Threshold and Data Analysis on Human MOG Antibody Detection by Live Flow Cytometry

Human autoantibodies targeting myelin oligodendrocyte glycoprotein (MOG Ab) have become a useful clinical biomarker for the diagnosis of a spectrum of inflammatory demyelinating disorders. Live cell-based assays that detect MOG Ab against conformational MOG are currently the gold standard. Flow cyto...

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Detalles Bibliográficos
Autores principales: Tea, Fiona, Pilli, Deepti, Ramanathan, Sudarshini, Lopez, Joseph A., Merheb, Vera, Lee, Fiona X. Z., Zou, Alicia, Liyanage, Ganesha, Bassett, Chelsea B., Thomsen, Selina, Reddel, Stephen W., Barnett, Michael H., Brown, David A., Dale, Russell C., Brilot, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016080/
https://www.ncbi.nlm.nih.gov/pubmed/32117270
http://dx.doi.org/10.3389/fimmu.2020.00119