Ticagrelor Enhances Release of Anti-Hypoxic Cardiac Progenitor Cell-Derived Exosomes Through Increasing Cell Proliferation In Vitro

Despite the widespread clinical use of cardioprotection by long-term direct antagonism of P2Y12 receptor, underlying mechanisms are unclear. Here, we identify how release of pro-survival exosomes from human cardiac-derived mesenchymal progenitor cells (hCPCs) is regulated by clinically relevant dose...

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Detalles Bibliográficos
Autores principales: Casieri, Valentina, Matteucci, Marco, Pasanisi, Emilio M., Papa, Angela, Barile, Lucio, Fritsche-Danielson, Regina, Lionetti, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016113/
https://www.ncbi.nlm.nih.gov/pubmed/32051439
http://dx.doi.org/10.1038/s41598-020-59225-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016113/
https://www.ncbi.nlm.nih.gov/pubmed/32051439
http://dx.doi.org/10.1038/s41598-020-59225-7

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