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Ticagrelor Enhances Release of Anti-Hypoxic Cardiac Progenitor Cell-Derived Exosomes Through Increasing Cell Proliferation In Vitro
Despite the widespread clinical use of cardioprotection by long-term direct antagonism of P2Y12 receptor, underlying mechanisms are unclear. Here, we identify how release of pro-survival exosomes from human cardiac-derived mesenchymal progenitor cells (hCPCs) is regulated by clinically relevant dose...
Autores principales: | Casieri, Valentina, Matteucci, Marco, Pasanisi, Emilio M., Papa, Angela, Barile, Lucio, Fritsche-Danielson, Regina, Lionetti, Vincenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016113/ https://www.ncbi.nlm.nih.gov/pubmed/32051439 http://dx.doi.org/10.1038/s41598-020-59225-7 |
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