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(−)-Epigallocatechin gallate inhibits stemness and tumourigenicity stimulated by AXL receptor tyrosine kinase in human lung cancer cells

Cancer stem cells (H1299-sdCSCs) were obtained from tumour spheres of H1299 human lung cancer cells. We studied low stiffness, a unique biophysical property of cancer cells, in H1299-sdCSCs and parental H1299. Atomic force microscopy revealed an average Young’s modulus value of 1.52 kPa for H1299-sd...

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Detalles Bibliográficos
Autores principales: Namiki, Kozue, Wongsirisin, Pattama, Yokoyama, Shota, Sato, Motoi, Rawangkan, Anchalee, Sakai, Ryo, Iida, Keisuke, Suganuma, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016176/
https://www.ncbi.nlm.nih.gov/pubmed/32051483
http://dx.doi.org/10.1038/s41598-020-59281-z