Evolutionary Origin of the P2X7 C-ter Region: Capture of an Ancient Ballast Domain by a P2X4-Like Gene in Ancient Jawed Vertebrates

P2X purinergic receptors are extracellular ATP-gated ion channel receptors present on the cell plasma membrane. P2X receptors have been found in Metazoa, fungi, amoebas, and in plants. In mammals, P2X7 is expressed by a large number of cell types and is involved in inflammation and immunity. Remarka...

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Detalles Bibliográficos
Autores principales: Rump, Airi, Smolander, Olli Pekka, Rüütel Boudinot, Sirje, Kanellopoulos, Jean M., Boudinot, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016195/
https://www.ncbi.nlm.nih.gov/pubmed/32117264
http://dx.doi.org/10.3389/fimmu.2020.00113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016195/
https://www.ncbi.nlm.nih.gov/pubmed/32117264
http://dx.doi.org/10.3389/fimmu.2020.00113

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