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Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis

BACKGROUND: Previously, we found that amplification of chromosome 17q24.1-24.2 is associated with lymph node metastasis, tumour size, and lymphovascular invasion in invasive ductal carcinoma. A gene within this amplicon, CACNG4, an L-type voltage-gated calcium channel gamma subunit, is elevated in b...

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Detalles Bibliográficos
Autores principales: Kanwar, Nisha, Carmine-Simmen, Katia, Nair, Ranju, Wang, Chunjie, Moghadas-Jafari, Soode, Blaser, Heiko, Tran-Thanh, Danh, Wang, Dongyu, Wang, Peiqi, Wang, Jenny, Pasculescu, Adrian, Datti, Alessandro, Mak, Tak, Lewis, John D., Done, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016384/
https://www.ncbi.nlm.nih.gov/pubmed/32062352
http://dx.doi.org/10.1016/j.ebiom.2020.102646