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Differential effects of integrin-linked kinase inhibitor Cpd22 on severe pulmonary hypertension in male and female rats

Pulmonary arterial hypertension (PAH) is a progressive fatal disease with no cure. Inhibition of integrin-linked kinase (ILK) reverses experimental pulmonary hypertension (PH) in male mice, but its effect on severe experimental PH in either male or female animals is unknown. We examined effects of I...

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Detalles Bibliográficos
Autores principales: Shen, Yuanjun, Goncharov, Dmitry A., Avolio, Theodore, Ray, Arnab, Okorie, Evelyn, DeLisser, Horace, Mora, Ana L., Vanderpool, Rebecca, Kudryashova, Tatiana V., Goncharova, Elena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016388/
https://www.ncbi.nlm.nih.gov/pubmed/32110386
http://dx.doi.org/10.1177/2045894019898593