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B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer’s Patches

Antibodies secreted within the intestinal tract provide protection from the invasion of microbes into the host tissues. Germinal center (GC) formation in lymph nodes and spleen strictly requires SLAM-associated protein (SAP)-mediated T cell functions; however, it is not known whether this mechanism...

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Detalles Bibliográficos
Autores principales: Biram, Adi, Winter, Eitan, Denton, Alice E., Zaretsky, Irina, Dassa, Bareket, Bemark, Mats, Linterman, Michelle A., Yaari, Gur, Shulman, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016508/
https://www.ncbi.nlm.nih.gov/pubmed/32049020
http://dx.doi.org/10.1016/j.celrep.2020.01.032