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RNA-Based Therapeutics: From Antisense Oligonucleotides to miRNAs
The first therapeutic nucleic acid, a DNA oligonucleotide, was approved for clinical use in 1998. Twenty years later, in 2018, the first therapeutic RNA-based oligonucleotide was United States Food and Drug Administration (FDA) approved. This promises to be a rapidly expanding market, as many emergi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016530/ https://www.ncbi.nlm.nih.gov/pubmed/31936122 http://dx.doi.org/10.3390/cells9010137 |