Serial Xenotransplantation in NSG Mice Promotes a Hybrid Epithelial/Mesenchymal Gene Expression Signature and Stemness in Rhabdomyosarcoma Cells

Serial xenotransplantation of sorted cancer cells in immunodeficient mice remains the most complex test of cancer stem cell (CSC) phenotype. However, we have demonstrated in various sarcomas that putative CSC surface markers fail to identify CSCs, thereby impeding the isolation of CSCs for subsequen...

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Detalles Bibliográficos
Autores principales: Skoda, Jan, Neradil, Jakub, Staniczkova Zambo, Iva, Nunukova, Alena, Macsek, Peter, Borankova, Karolina, Dobrotkova, Viera, Nemec, Pavel, Sterba, Jaroslav, Veselska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016569/
https://www.ncbi.nlm.nih.gov/pubmed/31941033
http://dx.doi.org/10.3390/cancers12010196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016569/
https://www.ncbi.nlm.nih.gov/pubmed/31941033
http://dx.doi.org/10.3390/cancers12010196

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