Nanoparticles Loaded with the BET Inhibitor JQ1 Block the Growth of Triple Negative Breast Cancer Cells In Vitro and In Vivo

Inhibition of bromo-and extra-terminal domain (BET) proteins, epigenetic regulators of genes involved in cell viability, has been efficiently tested in preclinical models of triple negative breast cancer (TNBC). However, the use of the selective BET-inhibitor JQ1 on humans is limited by its very sho...

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Detalles Bibliográficos
Autores principales: Maggisano, Valentina, Celano, Marilena, Malivindi, Rocco, Barone, Ines, Cosco, Donato, Mio, Catia, Mignogna, Chiara, Panza, Salvatore, Damante, Giuseppe, Fresta, Massimo, Andò, Sebastiano, Russo, Diego, Catalano, Stefania, Bulotta, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016573/
https://www.ncbi.nlm.nih.gov/pubmed/31905936
http://dx.doi.org/10.3390/cancers12010091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016573/
https://www.ncbi.nlm.nih.gov/pubmed/31905936
http://dx.doi.org/10.3390/cancers12010091

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