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Nanoparticles Loaded with the BET Inhibitor JQ1 Block the Growth of Triple Negative Breast Cancer Cells In Vitro and In Vivo
Inhibition of bromo-and extra-terminal domain (BET) proteins, epigenetic regulators of genes involved in cell viability, has been efficiently tested in preclinical models of triple negative breast cancer (TNBC). However, the use of the selective BET-inhibitor JQ1 on humans is limited by its very sho...
Autores principales: | Maggisano, Valentina, Celano, Marilena, Malivindi, Rocco, Barone, Ines, Cosco, Donato, Mio, Catia, Mignogna, Chiara, Panza, Salvatore, Damante, Giuseppe, Fresta, Massimo, Andò, Sebastiano, Russo, Diego, Catalano, Stefania, Bulotta, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016573/ https://www.ncbi.nlm.nih.gov/pubmed/31905936 http://dx.doi.org/10.3390/cancers12010091 |
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