Nicotine Induces Polyspermy in Sea Urchin Eggs through a Non-Cholinergic Pathway Modulating Actin Dynamics

While alkaloids often exert unique pharmacological effects on animal cells, exposure of sea urchin eggs to nicotine causes polyspermy at fertilization in a dose-dependent manner. Here, we studied molecular mechanisms underlying the phenomenon. Although nicotine is an agonist of ionotropic acetylchol...

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Detalles Bibliográficos
Autores principales: Limatola, Nunzia, Vasilev, Filip, Santella, Luigia, Chun, Jong Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016604/
https://www.ncbi.nlm.nih.gov/pubmed/31881774
http://dx.doi.org/10.3390/cells9010063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016604/
https://www.ncbi.nlm.nih.gov/pubmed/31881774
http://dx.doi.org/10.3390/cells9010063

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