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The Mitotic Apparatus and Kinetochores in Microcephaly and Neurodevelopmental Diseases
Regulators of mitotic division, when dysfunctional or expressed in a deregulated manner (over- or underexpressed) in somatic cells, cause chromosome instability, which is a predisposing condition to cancer that is associated with unrestricted proliferation. Genes encoding mitotic regulators are grow...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016623/ https://www.ncbi.nlm.nih.gov/pubmed/31878213 http://dx.doi.org/10.3390/cells9010049 |