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Prediction of Drug Efficacy in Colon Cancer Preclinical Models Using a Novel Ranking Method of Gene Expression

The presence of stromal cells in tumors is altering the significance of molecular profiling when using standard methods of gene expression quantification. We developed a novel normalization method to rank target gene expression in tumor samples by comparisons with reference samples representing the...

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Detalles Bibliográficos
Autores principales: Fritz, Justine, Lefebvre, Olivier, Fernandez, Aurore, Schmidt, Jordane, Bagnard, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016638/
https://www.ncbi.nlm.nih.gov/pubmed/31936310
http://dx.doi.org/10.3390/cancers12010149