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Sphingosine 1-Phosphate Receptor 2 Induces Otoprotective Responses to Cisplatin Treatment

Ototoxicity is a major adverse effect of platinum-based chemotherapeutics and currently, there remains a lack of United States Food and Drug Administration-approved therapies to prevent or treat this problem. In our study, we examined the role of the sphingosine 1-phosphate receptor 2 (S1P(2)) in at...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Shanmugam, Muthu K., Xiang, Ping, Yam, Ting Yu Amelia, Kumar, Vineet, Chew, Wee Siong, Chang, Jing Kai, Ali, Muhammad Zulfaqar Bin, Reolo, Marie J. Y., Peh, Yee Xin, Abdul Karim, Siti Nasuha Binte, Tan, Andrew Y.Y., Sanda, Takaomi, Sethi, Gautam, Herr, Deron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016659/
https://www.ncbi.nlm.nih.gov/pubmed/31952197
http://dx.doi.org/10.3390/cancers12010211