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Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients

Background: Marfan syndrome (MFS) is a genetic disease, characterized by thoracic aortic aneurysm (TAA), which treatment is to date purely surgical. Understanding of novel molecular targets is mandatory to unveil effective pharmacological approaches. Cyclophilin A (CyPA) and its receptor EMMPRIN are...

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Detalles Bibliográficos
Autores principales: Perrucci, Gianluca L., Rurali, Erica, Corlianò, Maria, Balzo, Maria, Piccoli, Michela, Moschetta, Donato, Pini, Alessandro, Gaetano, Raffaella, Antona, Carlo, Egea, Gustavo, Fischer, Gunter, Malešević, Miroslav, Alamanni, Francesco, Cogliati, Elisa, Paolin, Adolfo, Pompilio, Giulio, Nigro, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016677/
https://www.ncbi.nlm.nih.gov/pubmed/31936351
http://dx.doi.org/10.3390/cells9010154