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Rap1 Is Involved in Angiopoietin-1-Induced Cell-Cell Junction Stabilization and Endothelial Cell Sprouting

Angiopoietin-1 (Ang-1) is an important proangiogenic factor also involved in the maintenance of endothelial-barrier integrity. The small GTPase Rap1 is involved in the regulation of adherens junctions through VE-cadherin-mediated adhesion, and in endothelial permeability. While many studies establis...

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Detalles Bibliográficos
Autores principales: Gaonac’h-Lovejoy, Vanda, Boscher, Cécile, Delisle, Chantal, Gratton, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016689/
https://www.ncbi.nlm.nih.gov/pubmed/31936361
http://dx.doi.org/10.3390/cells9010155