Cargando…

RhoA-GTPase Modulates Neurite Outgrowth by Regulating the Expression of Spastin and p60-Katanin

RhoA-GTPase (RhoA) is widely regarded as a key molecular switch to inhibit neurite outgrowth by rigidifying the actin cytoskeleton. However, during neurite outgrowth, whether and how microtubule dynamics are regulated by RhoA remains to be elucidated. Herein, CT04 and Y27632 were used to inactivate...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Dandan, Zhang, Haowen, Deng, Junyao, Liu, Jingmin, Wen, Jinkun, Li, Lixia, Wang, Xianghai, Pan, Mengjie, Hu, Xiaofang, Guo, Jiasong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016723/
https://www.ncbi.nlm.nih.gov/pubmed/31963385
http://dx.doi.org/10.3390/cells9010230