Candidate Causal Variants at the 8p12 Breast Cancer Risk Locus Regulate DUSP4

Genome-wide association studies have revealed a locus at 8p12 that is associated with breast cancer risk. Fine-mapping of this locus identified 16 candidate causal variants (CCVs). However, as these variants are intergenic, their function is unclear. To map chromatin looping from this risk locus to...

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Detalles Bibliográficos
Autores principales: Glubb, Dylan M., Shi, Wei, Beesley, Jonathan, Fachal, Laura, Pritchard, Jayne-Louise, McCue, Karen, Barnes, Daniel R., Antoniou, Antonis C., Dunning, Alison M., Easton, Douglas F., Chenevix-Trench, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016765/
https://www.ncbi.nlm.nih.gov/pubmed/31936698
http://dx.doi.org/10.3390/cancers12010170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016765/
https://www.ncbi.nlm.nih.gov/pubmed/31936698
http://dx.doi.org/10.3390/cancers12010170

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