Engineering and Characterization of Oncolytic Vaccinia Virus Expressing Truncated Herpes Simplex Virus Thymidine Kinase

Oncolytic viruses are a promising class of anti-tumor agents; however, concerns regarding uncontrolled viral replication have led to the development of a replication-controllable oncolytic vaccinia virus (OVV). The engineering involves replacing the native thymidine kinase (VV-tk) gene, in a Wyeth s...

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Detalles Bibliográficos
Autores principales: Islam, S. M. Bakhtiar Ul, Lee, Bora, Jiang, Fen, Kim, Eung-Kyun, Ahn, Soon Cheol, Hwang, Tae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016767/
https://www.ncbi.nlm.nih.gov/pubmed/31963415
http://dx.doi.org/10.3390/cancers12010228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016767/
https://www.ncbi.nlm.nih.gov/pubmed/31963415
http://dx.doi.org/10.3390/cancers12010228

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