Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages

Silicosis is an occupational lung disease characterized by persistent inflammation and irreversible fibrosis. Crystalline silica (CS) particles are mainly phagocytized by alveolar macrophages (AMs), which trigger apoptosis, inflammation, and pulmonary fibrosis. Previously, we found that autophagy-ly...

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Detalles Bibliográficos
Autores principales: He, Xiu, Chen, Shi, Li, Chao, Ban, Jiaqi, Wei, Yungeng, He, Yangyang, Liu, Fangwei, Chen, Ying, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016807/
https://www.ncbi.nlm.nih.gov/pubmed/31947943
http://dx.doi.org/10.3390/cells9010122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016807/
https://www.ncbi.nlm.nih.gov/pubmed/31947943
http://dx.doi.org/10.3390/cells9010122

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