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The Reverse Warburg Effect Is Associated with Fbp2-Dependent Hif1α Regulation in Cancer Cells Stimulated by Fibroblasts

Fibroblasts are important contributors to cancer development. They create a tumor microenvironment and modulate our metabolism and treatment resistance. In the present paper, we demonstrate that healthy fibroblasts induce metabolic coupling with non-small cell lung cancer cells by down-regulating th...

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Detalles Bibliográficos
Autores principales: Duda, Przemysław, Janczara, Jakub, McCubrey, James A., Gizak, Agnieszka, Rakus, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016812/
https://www.ncbi.nlm.nih.gov/pubmed/31947613
http://dx.doi.org/10.3390/cells9010205