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Elevated Expression of Lumican in Lung Cancer Cells Promotes Bone Metastasis through an Autocrine Regulatory Mechanism

Background: The microarray analysis of whole-genome expression indicated that the gene encoding the protein lumican, which is associated with extracellular matrix (ECM) interaction, was highly expressed in osteotropic lung cancer cell lines with an enhanced capacity of bone metastasis. Methods: The...

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Detalles Bibliográficos
Autores principales: Hsiao, Kuan-Chung, Chu, Pei-Yi, Chang, Gee-Chen, Liu, Ko-Jiunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016828/
https://www.ncbi.nlm.nih.gov/pubmed/31963522
http://dx.doi.org/10.3390/cancers12010233