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Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis

Peroxiredoxins (Prxs) are a family of thioredoxin peroxidases. Accumulating evidence suggests that changes in the expression of Prxs may be involved in neurodegenerative diseases pathology. However, the expression and function of Prxs in Parkinson’s disease (PD) remains unclear. Here, we showed that...

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Detalles Bibliográficos
Autores principales: Wang, Mei-Jen, Huang, Hsin-Yi, Chiu, Tsung-Lang, Chang, Hui-Fen, Wu, Hsin-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016837/
https://www.ncbi.nlm.nih.gov/pubmed/31861721
http://dx.doi.org/10.3390/cells9010022