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Peroxiredoxin 5 Silencing Sensitizes Dopaminergic Neuronal Cells to Rotenone via DNA Damage-Triggered ATM/p53/PUMA Signaling-Mediated Apoptosis
Peroxiredoxins (Prxs) are a family of thioredoxin peroxidases. Accumulating evidence suggests that changes in the expression of Prxs may be involved in neurodegenerative diseases pathology. However, the expression and function of Prxs in Parkinson’s disease (PD) remains unclear. Here, we showed that...
Autores principales: | Wang, Mei-Jen, Huang, Hsin-Yi, Chiu, Tsung-Lang, Chang, Hui-Fen, Wu, Hsin-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016837/ https://www.ncbi.nlm.nih.gov/pubmed/31861721 http://dx.doi.org/10.3390/cells9010022 |
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