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Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling

The Janus kinase-signal transducer and activator of transcription protein (JAK-STAT) pathway mediates essential biological functions from immune responses to haematopoiesis. Deregulated JAK-STAT signaling causes myeloproliferative neoplasms, leukaemia, and lymphomas, as well as autoimmune diseases....

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Detalles Bibliográficos
Autores principales: Raivola, Juuli, Haikarainen, Teemu, Silvennoinen, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016850/
https://www.ncbi.nlm.nih.gov/pubmed/31892268
http://dx.doi.org/10.3390/cancers12010078